255 research outputs found

    The value of other people's health: individual models and motives for helping

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    This thesis was motivated by a wish to understand the slow response to HIV/AIDS and so seeks to address the questions of why and when people help others. The questions are important, as typically it is others who decide who among those most in need receive help. To narrow the focus to motives of help, the discussions consider the helping of distant others, as typically such actions do not involve material gain to the helper. Related literature exists on charitable behaviour but tends towards a marketing approach. This limits its use in providing specific input regarding motives. The economics literature is far more specific and a review identifies four groups of models. These models have a number of weaknesses, so an alternative is suggested: the balance model, and a responsibility formulation, is proposed for this and existing models, which, it is argued, assist in addressing the questions. Following on from the identification and development of alternative theoretical frameworks, these options are taken through a process of attrition. They are contrasted with evidence and theory from the psychology literature - first on helping and then on harming. This exercise suggests the relative strength of the balance model and the maintenance of a responsible self-image model. Both deal well with explaining how help differs according to context and how individuals might avoid or deliberately misinterpret information. The balance model is used to examine individual helping behaviour, by way of an economic experiment. The model is then expanded to consider the social context, which allows for the consideration of the HIV response. The theoretical discussions and the experimental results suggest that individuals feel a responsibility to help. They can, however, try to avoid information which may prompt such feelings and manipulate themselves to reduce the pressure such feelings place on them to help

    Desmond Chris- Callison College One Pager

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    https://scholarlycommons.pacific.edu/callison-college-sis/1024/thumbnail.jp

    Men, families and HIV/AIDS

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    The dual role of income in the spread of HIV in Africa.

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    Thesis (M.Com.)-University of Natal, Durban, 2002.Every day more people in Africa are infected with HIV despite prevention efforts. These new infections and those already infected are not evenly spread throughout the continent. Substantial variations in HIV prevalence exist within and between countries. Understanding these variations helps understand what is driving the epidemic and this understanding in turn helps in the design of more appropriate interventions to prevent its further spread. This thesis builds on existing work by attempting to develop a more comprehensive theory of what role income plays in the spread of HIV. To this end the Theory of the Dual Role of Income in the Spread of HIV is outlined and explained. It uses the concepts of relative and absolute income, borrowed from elsewhere in the health economics literature, to separate the different effects income has on individual and group risk of HIV infection. The theory hypothesises that, while higher levels of absolute income (income independent of others) offer protection against infection via better access to health care and information, higher relative income (the income of an individual relative to other members of their social or reference group) increases risk of infection either as a result of more sexual partners or higher risk partners. The theory in no way argues that HIV infections are not related to poverty, but rather that the relationship is, somewhat more complicated and non-linear than often suggested. The explanatory power of the theory is examined with the use primarily of two data sets: firstly using data collected from antenatal clinics in two South African provinces linked with census data and secondly with data on a large South African company. While these data are not ideal, the results from the analysis are in line with the expectations based on the theory. The theory and the results of the analysis presented in this thesis support the argument that environments in which decisions are made and actions taken are important in determining risk of HIV infection. This argument suggests that prevention efforts need to do more then provide information

    American Cyber Insecurity: The growing danger of cyber attacks

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    This paper aims to advise American policy makers on a correct course of action regarding the advent of cyber warfare. Cyber-attacks have become ubiquitous in the 21st century and pose a direct threat to the safety of American interests abroad and domestically. Beginning with an analysis of the history and lessons from past cyber conflicts this paper moves on to proscribe a set of actions to protect American security in the 21st century. We conclude that the current legal framework for evaluating cyber-attacks needs to be re-framed in a manner more conducive to American interests.Winner of the 2014 Alona E. Evans Prize, a Duke Political Science award for the undergraduate or graduate student(s) whose paper on international law best reflects excellence in scholarshi

    Universal molecular screening does not effectively detect Lynch syndrome in clinical practice

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    Background: Lynch syndrome (LS) due to an inherited damaging mutation in mismatch repair (MMR) genes comprises 3% of all incident colorectal cancer (CRC). Molecular testing using immunohistochemistry (IHC) for MMR proteins is a recommended screening tool to identify LS in incident CRC. This study assessed outcomes of population-based routine molecular screening for diagnosis of LS in a regional center. Methods: We conducted a prospective, consecutive case series study of universal IHC testing on cases of resected CRC from September 2004–December 2013. Referred cases with abnormal IHC results that attended a familial cancer clinic were assessed according to modified Bethesda criteria (until 2009) or molecular criteria (from 2009). Results: 1612 individuals underwent resection for CRC in the study period and had MMR testing by IHC. Of these, 274 cases (16.9%) exhibited loss of expression of MMR genes. The mean age at CRC diagnosis was 68.1 years (± standard deviation 12.7) and the mean age of those with an IHC abnormality was 71.6 (± 11.8). A total of 82 (29.9%) patients with an abnormal result were seen in a subspecialty familial cancer clinic. Patients aged under 50 (p = 0.009) and those with loss of MSH6 staining (p = 0.027) were more likely to be referred and to attend. After germ-line sequencing, 0.6% (10 of 82) were identified as having a clinically significant abnormality. A further eight probands with pathogenic germ-line mutations were identified from other referrals to the service over the same time period. Conclusions: While technically accurate, the yield of ‘universal’ IHC in detecting new Lynch probands is limited by real-world factors that reduce referrals and genetic testing. We propose an alternative approach for universal, incident case detection of Lynch syndrome with ‘one-stop’ MMR testing and sequencing.This work was supported by a grant from the Canberra Hospital Private Practice Fund (to DT)
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